Identification of in vivo, conserved, TAF15 RNA binding sites reveals the impact of TAF15 on the neuronal transcriptome

Summary

Using CLIP-seq, this study identifies the in vivo binding sites of TAF15, an ALS-associated RNA-binding protein, across the neuronal transcriptome. The findings reveal evolutionarily conserved binding sites and provide insight into the role of TAF15 in neuronal RNA metabolism.