MOV10L1 on Maragkakis Labhttp://maragkakislab.com/tags/mov10l1/Recent content in MOV10L1 on Maragkakis LabHugoen-usSun, 15 Mar 2015 00:00:00 +0000The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processinghttp://maragkakislab.com/publications/2015-mov10l1-pirna-processing/Sun, 15 Mar 2015 00:00:00 +0000http://maragkakislab.com/publications/2015-mov10l1-pirna-processing/<h2 id="summary">Summary</h2> <p>This study demonstrates that MOV10L1, a germline-specific RNA helicase, directly binds to piRNA precursors and is required for their processing into mature piRNAs. MOV10L1 acts upstream of Piwi proteins in the piRNA biogenesis pathway, providing mechanistic insight into piRNA production.</p>