Stress Response in Senescence and Aging

Understand the molecular mechanisms of stress response and cellular senescence using machine learning, long-read nanopore sequencing and ribosome profiling.

RNA Metabolism and Translation in Aging

Discover the dynamics of post-transcriptional modulators of aging using long-read single-cell sequencing, spatial transcriptomics, and statistical modeling

RNA Processing in Aging-Associated Disease

Discover the role of RNA-binding proteins (RBPs) in mRNA processing and alternative splicing in neurodegeneration, and provide high-quality long-read transcriptomic resources through large collaborative initiatives.